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Instead, the team kept finding hints that brain tissue from

Herpes Viruses And Alzheimer’s

Wholesale Replica Bags Two common herpes viruses appear to play a role in Alzheimer’s disease. Wholesale Replica Bags

replica Purse The viruses, best known for causing a distinctive skin rash in young children, are abundant in brain tissue from people with Alzheimer’s, a team of scientists reports luxury replica bags Thursday in Neuron. The team also found evidence that the viruses can interact with brain cells good quality replica bags in ways designer replica luggage that could accelerate the disease. Sinai replica bags china in New York City. replica Purse

aaa replica designer handbags The finding adds credence to a decades old idea high end replica bags that an infection can cause Alzheimer’s disease. It also suggests that it may be possible to prevent or slow Alzheimer’s using antiviral drugs, or drugs that modulate how immune cells in the brain respond to an infection. aaa replica designer handbags

KnockOff Handbags But the study doesn’t prove that herpes viruses are involved in buy replica bags online Alzheimer’s, says Dr. Richard Hodes, director of the National Institute on Aging, which helped fund the research. KnockOff Handbags

“The data are very provocative, but fall short of showing a direct causal role,” he says. “And if 7a replica bags wholesale viral infections are playing a part, they are not the sole actor.”

Even high quality designer replica so, the study offers strong evidence that viral infections can influence the course of Alzheimer’s, Hodes says.

Designer Fake Bags Like a lot of scientific discoveries, this one best replica bags replica designer bags wholesale was an aaa replica bags accident. “Viruses were the last thing we were looking for,” Dudley says. Designer Fake Bags

Replica Bags He and a team of researchers were using genetic data to look for differences between healthy brain tissue and brain tissue from people bag replica high quality who died with Alzheimer’s. Replica Bags

The goal was to identify new targets for drugs. Instead, the team kept finding hints that brain tissue from Alzheimer’s patients contained higher levels of viruses.

“When we started analyzing the replica bags buy online differences, it high replica bags just sort of came screaming out at us from the data,” Dudley says.

cheap replica handbags The team found that levels of two human herpes viruses, HHV 6 and HHV 7, were up to twice as high in replica wallets brain tissue from people with Alzheimer’s. They confirmed the finding by analyzing replica designer backpacks data from a consortium of brain replica designer bags banks. cheap replica handbags

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These herpes viruses are extremely common, and can cause a skin rash best replica designer bags called roseola in young children. But the viruses also can get into cheap designer bags replica the brain, where they may remain inactive for decades.

purse replica handbags Once the researchers knew the viruses were associated with Alzheimer’s they started trying to figure out how a virus could affect the course of a brain disease. That meant identifying interactions between the virus genes and other genes in brain cells. purse replica handbags

Replica Handbags “We mapped out the social network, if you will, of which genes the viruses are friends with and who they’re talking to inside the brain,” Dudley says. In essence, he says, they wanted to know: “If the viruses are tweeting, who’s tweeting back?” Replica Handbags

replica handbags china And what they high quality replica bags found was that the herpes virus genes were interacting with genes known to increase a person’s risk for Alzheimer’s. replica handbags china

They also found that these Alzheimer’s risk genes seem to make a person’s brain more vulnerable to infection with the two herpes viruses.

Handbags Replica But just having herpes virus present in the brain isn’t enough to cause Alzheimer’s, Dudley says. Something needs to activate the viruses, which causes them to begin replicating. Handbags Replica

wholesale replica designer handbags It’s not clear what causes the activation, Dudley says, though he suspects some sort of change in the https://www.replicawest.com best replica bags internal functions of brain cells. wholesale replica designer handbags

Designer Replica Bags Once the viruses do become active, they appear to influence things like the accumulation of the plaques and tangles in the brain associated with Alzheimer’s. “They are sort of throwing a replica bags online wrench in the works,” he says. Designer Replica Bags

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Brain’s Link To Immune System Might Help Explain Alzheimer’s

high quality replica handbags The herpes viruses also seem to trigger an immune response in certain brain cells, Hodes says. These cells are part of an ancient immune system that has previously been implicated in Alzheimer’s. high quality replica handbags

Most previous efforts to prevent or treat Alzheimer’s have involved best replica designer trying to reduce the plaques and tangles associated with the disease. Those efforts have failed to improve brain function even when they accomplished their immediate goal.

replica handbags online Those replica bags “distressing and disappointing failures” suggest it’s time for some new approaches, Hodes says. And the new study suggests at least two. replica handbags online

One is to give antiviral drugs to people with high levels of herpes replica bags from china virus in their brains. The Institute on Aging is already funding a study to test this approach buy replica bags in people in the early stages of Alzheimer’s, Hodes says.

Another approach is to prevent the brain’s immune cells from reacting to the virus in ways that accelerate Alzheimer’s, Hodes says. That’s tricky, he says, because simply disabling the brain’s immune cells could be harmful.

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